KMID : 0644120060190040077
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Journal of Oriental Gynecology 2006 Volume.19 No. 4 p.77 ~ p.92
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Effects of Woogwiyeum on the Ovariectomized Rat Model of Postmenopausal Osteoporosis
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Choe Chang-Min
Lee Su-Jeong
Kim Song-Baeg Cho Han-Baek
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Abstract
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Purpose : This study is to examine what are the effects of the Woogwiyeum(WGY) on the ovariectomized rat model of postmenopausal osteoporosis.
Methods : We devide mice to 3 Group(Sham operated group, control group, WGY treated group) and analyze each serum component.
Results : 1. Body weight in control group showed significant increase in comparison with sham, but that in WGY-treated showed no change in comparison with control. 2. The level of serum albumin, ALP in control group showed significant decrease in comparison with sham. That in WGY-treated was decreased in comparison with control. 3. Trabecular bone area as well as trabecular thickness in control group showed significant decrease in comparison with sham. Those in WGY-treated showed significant increase in comparison with control. 4. Osteoclast number and oseoblast surface in control group showed significant increase in comparison with sham. Those in WGY-treated showed significant decrease in comparison with control.
Conclusion : WGY has shown to be capable of preventing and curing osteoporosis caused by old-aged and postmenopause.
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KEYWORD
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Woogwiyeum(WGY), postmenopause, Osteoporosis
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